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PROVISIONAL PROGRAM

International Scientific Conference: Cancer & Epigenetics – Paris, November 28, 2025

The Cancer & Epigenetics 2025 scientific conference will take place on Friday, November 28 at the Constant Burg Amphitheater, Institut Curie (12 rue Lhomond, 75005 Paris, France). Organized by SIRIC Curie (Institut Curie) and SIRIC EpiCure (Gustave Roussy), this high-level international event is coordinated by
Dr. Céline Vallot and Dr. Sophie Postel-Vinay.

The program will include keynote presentations, a poster session, an exhibition area, and multiple opportunities for networking and collaboration. Join us for this unmissable day focused on the latest advances in cancer epigenetics. The symposium will bring together leading researchers across four major thematic sessions:

8.20-8.30
AM
Dr Céline Vallot & Dr Sophie Postel-Vinay
SIRIC Curie/ SIRIC EpiCure
Welcome and introduction
    8.30-10.00
    AM

    Session I

    Targeting Transcription Factors
      8.30-9.00
      AM
      Pr Olivier Delattre, Institut Curie, FR
      Gene fusions in cancer, from genetics to immunology
        9.00-9.30
        AM
        Dr Chris Marine, VIB-KU, B
        Nongenetic mechanisms of melanoma evolution and therapy resistance
          9.30-10.00
          AM
          Dr Nicolas Bery, CRCT, FR
          Targeting hard-to-drug proteins with intracellular antibodies
            10.00-10.30
            AM
            Coffee break and exhibition
              10.00-14.00
              AM

              Session II

              Epigenetic vulnerabilities
                10.30-11.00
                AM
                Dr Stefan Kubicek, CEMM, AT
                Targeting chromatin processes via their subcellular localization
                  11.00-11.30
                  AM
                  Dr Gabriel Malouf, IGBMC, FR
                  Epigenetic Alterations as Biomarkers and Therapeutic Targets in Renal Cell Carcinomas
                    11.30-12.00
                    AM
                    Dr Mehdi Touat, Siric Curamus, FR
                    Novel patterns of high-grade transformation in IDH-mutant gliomas
                      12.00-02.00
                      PM
                      Lunch break, exhibition and poster session
                        02.00-04.00
                        PM

                        Session III

                        Immuno-epigenetics
                          02.00-02.30
                          PM
                          Pr Daniel De Carvalho, University of Toronto, CA
                          Epigenetic deregulation of retroelements as a tumor suppressor mechanism and an emerging therapeutic opportunity
                            02.30-3.00
                            PM
                            Dr Erez Levanon, Bar-Ilan University, IS
                            A-to-I RNA Editing in Cancer
                              03.00-03.30
                              PM
                              Pr Stéphane Depil, CLB, FR
                              “Dark genome” and “dark antigens” : probably misnomers but promising targets for cancer im- munotherapy
                                03.30-04.00
                                PM
                                Dr Nada Jabado, McGill University, CA
                                Oncohistones: Lessons in Hijacking Chromatin Architecture
                                  04.00-04.30
                                  PM
                                  Coffee break and exhibition
                                    04.00-05h30
                                    PM

                                    Session IV

                                    Next challenges in cancer epigenetics
                                      04.30-05.00
                                      PM
                                      Dr Franco Izzo, Icahn School of Medicine at Mount Sinai, USA
                                      Genotype to phenotype mapping of human cancers through single-cell multi-omics
                                        05.00-05.30
                                        PM
                                        Dr Rong Fan, Yale School of Medicine USA
                                        Spatially Decoding RNA Regulation and Epigenetics in Human Clinical Archival FFPE Tissues
                                          05.30-06.00
                                          PM
                                          Dr Ekta Khurana, Weill Cornell Medicine, USA
                                          Non-neuroendocrine lineage plasticity in prostate cancer

                                            SPEAKERS

                                            Nicolas Bery
                                            CRCT, France